Cyactiv is a proprietary phycocyanin extract from spirulina. Phycocyanin is the blue pigment in blue-green algae and is a potent active compound proven to help balance and calm systemic
inflammation associated with a myriad of health issues. Balancing whole-body inflammation
assists the homing of stem cells to affected tissues.
Cyactiv: Balance and Calm Whole-Body Inflammation
Phycocyanin works as a selective inhibitor of COX-2 while a non-phycocyanin fraction of spirulina called LoxDown, works as an inhibitor of 5-LOX. Therefore, Cyactiv is a unique product to manage systemic inflammation.
- Cyactiv contains Phycocyanin concentrated extract from Spirulina shown to inhibit the enzyme COX-2 (cyclooxygenase) which is important in inflammation management.
- Cyactiv contains LoxDown, documented to inhibit 5-LOX (5-lipoxygenase) an enzyme that plays a key role in increased inflammation.
- Cyactiv supports the ability of stem cells to find and rejuvenate tissues in need of renewal.
- Cyactiv helps neutralize existing free radicals.
- Cyactiv provides cellular protection against the formation of new oxidative stress.
- Cyactiv FAQ
'Inflammation, from the Latin word inflamma, meaning fire, is associated with many illnesses, including depression and dementia. Just as poor blood flow is devastating to brain function, so is chronic inflammation in your body.'
- Daniel Amen, M.D.
Cyactiv Proven Clinical StudiesCyactiv is the result of 7 years of research and development and includes 4 human clinical trials and numerous in-vitro studies. Key data:
Cells treated with Cyactiv prior to exposure to an inflammatory insult resulted in the production of less free radicals than cells not exposed to Cyactiv.
Results from a randomized, double-blind, placebo-controlled, parallel-arm study. The graph above shows the reduction in discomfort during physical activity after 2 weeks of consuming either placebo or Cyactiv (1 gram/day). Each study participant's anatomical area of discomfort was identified at study start and tracked at later visits.
Antioxidant and Anti-Inflammatory Properties of an Aqueous Cyanophyta Extract study published in the Journal of Medicinal Food.
'This and other studies show that supplementation with Cyactiv can lead to a clinically meaningful effect as an antioxidant and anti-inflammatory alternative. The natural synergy of the phycocyanin and non-phycocyanin compounds help calm and balance recurring inflammation without the known side effects of nonsteroidal anti-inflammatory drugs.'
- Cassandra Drapeau, Product Manager, Cerule.
Clinical Safety of a High Dose of Phycocyanin-Enriched Aqueous Extract from Arthrospira (Spirulina) platensis: Results from a Randomized, Double-Blind, Placebo-Controlled Study with a Focus on Anticoagulant Activity and Platelet Activation. Published in the Journal of Medicinal Food.
Medical Application of Spirulina platensis Derived C-Phycocyanin. Published in the Journal of Evidence-Based Complementary and Alternative Medicine.
Health Benefits of Blue-Green Algae: Prevention of Cardiovascular Disease and Nonalcoholic Fatty Liver Disease. Published in the Journal of Medicinal Food.
Spirulina and C-phycocyanin reduce cytotoxicity and inflammation-related genes expression of microglial cells. Published in the Journal of Nutritional Neuroscience.
A Novel Phycobiliprotein Alleviates Allergic Airway Inflammation by Modulating Immune Responses. Published in the American Journal of Respiratory and Critical Care Medicine.
Antiinflammatory and antihyperalgesic activity of C-phycocyanin. Published in the Journal of Anesthesia & Analgesia.
C-Phycocyanin: A Biliprotein with Antioxidant, Anti-Inflammatory and Neuroprotective Effects. Published in the Journal of Current Protein & Peptide Science.
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Cyactiv Frequently Asked Questions
What is Cyactiv?
Cyactiv is a proprietary phycocyanin extract from spirulina. Phycocyanin is the blue pigment in blue-green algae and is a potent active compound proven to help balance and calm systemic inflammation associated with a myriad of health issues. Balancing whole-body inflammation assists the homing of stem cells to affected tissues.
Is there a video explaining how Cyactiv works?
'Cyactiv is a simple, yet very powerful product. To understand what Cyactiv does in the body, we need to understand the process of inflammation.
Inflammation in the body was meant to be a very, very localized phenomenon. If you have a cut, or an injury, or an infection, locally, compounds are being released to increase the blood flow, to attract immune cells, to attract stem cells, so that all these cells can do their job locally, to repair the tissue. And when everything is repaired, everything is done, then everything goes back to normal. That's what inflammation was meant to be.
The problem comes when you get up in the morning and you've got some knee pain, a little bit of discomfort in your hip, a little bit of shoulder stiffness, stiffness in your neck.
When you start to have this, understand here that it's not the only places where you've got inflammation, it's just because you have pain receptors in these areas that you feel the discomfort.
But you don't have pain receptors in your arteries, in your lungs, or in your liver. So when you start to have inflammation in some areas of the body, then most likely you have it in a lot more areas.
And then it becomes what we call systemic inflammation. Meaning all these inflammatory compounds slowly accumulated in your blood stream and it becomes inflammation of the entire system. It's called systemic inflammation, it's also referred to as whole body inflammation and it's also called silent inflammation because you don't feel it. But when you have systemic inflammation, it has been associated in many studies to a whole slew of health problems.
it really prevents the body to function normally and to achieve optimal health. For one thing, it prevents stem cells to properly identify the tissues that are in need of repair. So when you've got inflammation and it's accumulated like this in the body, you can not repair properly, you can not repair optimally, your immune system cannot function optimally.
You need to be able to calm down the systemic inflammation and that is where Cyactiv is really a unique product. Cyactiv is a concentrate of phycocyanin from spirulina. Phycocyanin has been known for many many years to be a very specific blocker of Cox 2. Cox 2 is an enzyme that leads to the formation in the body of a whole slew of inflammatory compounds. So if we can block the enzyme Cox 2, we really help to calm down, to balance this inflammatory process in the body.
But as we produced Cyactiv and concentrated phycocyanin, we also discovered another compound in Cyactiv. We don't know exactly what it is, but we called it Lox down, because it specifically blocks another enzyme also involved in another path way of inflammation. This enzyme is called 5-Lox. By adding Cyactiv, capable of calming down these 2 different enzymatic pathways, we really have the best product that one can have to really calm down and balance overall inflammation in the body.
Cyactiv is really an ideal product to control inflammation, so that we can really assist and give stem cells optimal terrain to be able to identify all the tissues in need of repair and be able to go there and do their job of repair.
That's what Cyactiv does, to just clam down overall inflammation in the body.'
- Christian Drapeau, CSO, Cerule
Why is Cyactiv beneficial?
Cyactiv supports a healthy lifestyle and overall wellness through:
- Balancing a healthy inflammation response, helping to maintain inflammation within the normal range.
- Supports the ability of nutrients, oxygen and stem cells to find and rejuvenate tissues in need of renewal.
- Neutralizing existing free radicals.
- Providing cellular protection against the formation of new oxidative stress.
What are the ingredients in Cyactiv?
Cyactiv is a concentrated phycocyanin extract from spirulina. Scientists studying the health benefits of spirulina discovered that the blue pigment in blue-green algae, phycocyanin (PC), was shown to inhibit the enzyme COX-2 (cyclooxygenase) which is important in inflammation management. Cyactiv also contains a non-PC component that was documented to inhibit 5-LOX (5-lipoxygenase), another enzyme playing an important role in inflammation.
Cyactiv does not contain dairy, wheat, gluten, peanut, soy, corn, or allergens. There are no artificial flavors or colors. It is 100% vegetarian, non-GMO, and free from herbicides and pesticides.
Cyactiv Clinical Studies
Phycocyanin works as a selective inhibitor of COX-2, a key enzyme involved in inflammation. Cyactiv is the result of 7 years of research and development and includes 4 human clinical trials and numerous in-vitro studies. Read the study here
Is Cyactiv safe to consume over a long period of time?
A safety study confirmed that consumption of Cyactiv was not associated with any side-effects, including negative effects on the stomach, heart, kidney or liver function.
Cyactiv safely and effectively helps to support a healthy inflammation response, reduce systemic inflammation and discomfort, and inhibit free radicals.
What is inflammation?
Inflammation is a double-edged sword. While short-term inflammation is a necessary and healthy response to injury, recurring inflammation due to prolonged stressors can cause a healthy response to get stuck in an overactive cycle. If the body is unable to reset the balance, sustained inflammation can reduce the ability of stem cells to find affected tissues, compromising the body's ability to self-heal.
How do I take Cyactiv?
Suggested usage: 2 capsules daily with food, for adult consumption.
Can children consume Cyactiv?
The clinical studies were done on adult populations, therefore we recommend Cyactiv for adult consumption, but there are no contraindications for children.
Can pets consume Cyactiv?
Cyactiv is formulated for human consumption. We know of no reason that is may be harmful to pets. AFA and spirulina have been used in the pet nutrition industry for years. However, we have done no studies using the products for pet consumption. Please check with your veterinarian.
When will I notice a difference when taking Cyactiv?
During clinical trials, a noticeable change was noted as early as 3 days. Overall significant changes were observed and reported within 3 weeks of usage with continued improvement over time.
What is the Cyactiv capsule made from?
As stated on the label, the vegetarian capsule is made from hypromellose. Hypromellose is cellulose derivative or plant fiber.
Is Cyactiv certified Kosher and Halal?
Cyactiv's ingredients are certified Kosher and Halal.
What is the shelf-life of Cyactiv?
There is an expiration date at the bottom of each bottle. Cyactiv has a shelf life of 3 years from manufacturing. All bottles should be stored in a cool, dry place.
Can Cyactiv be consumed with other Cerule products and other nutrients?
Yes, the Cerule products can be consumed together and were designed to enhance the beneficial effects of each other. We know of no concerning interaction between the Cerule products and other nutritional supplements.
Are there any known nutrient-medication interactions?
We know of no potential interaction between Cyactiv and any medication. If you have any health condition and/or are using any medication then consult your attending health care provider before consuming any nutritional supplement.
For some people, due to their conditions and medications, they need to manage their intake of certain nutrients. Below are the amounts of naturally occurring nutrients found in the plant based ingredients within Cyactv:
Iron: 0.40 mg per 2 capsules
Iodine: 1.09 ug per 2 capsules
Sodium: 14 mg per 2 capsules
Why does the Cyactiv label state 'consult your physician if you are pregnant or nursing?'
Pregnancy and nursing are considered special conditions. We recommend that your attending Doctor(s) be made aware of any and all supplements consumed during this time. At this time, we do not advise Cyactiv consumption during pregnancy.