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StemEnhance Ultra: The #1 in Stem Cell Nutrition

StemEnhance Ultra concentrates and combines extracts from nature's most primitive superfoods, fresh water microalgae and marine macroalgae, providing the body with the ultimate in stem cell support.

New formulation with the original StemEnhance, extracted from Lake Klamath harvested blue-green algae (AFA).

StemEnhance Ultra, made from Lake Klamath harvested blue-green algae

  • StemEnhance Ultra concentrates and combines extracts from nature's most primitive superfoods, freshwater microalgae and marine macroalgae, proving the body with the ultimate in stem cell support.

  • StemEnhance Ultra is backed by years of identifying, refining, and extracting compounds using proprietary and patented technologies.

  • The blending of StemEnhance Ultra with Fucoidan offers a unique synergy that is further enhanced by Mesenkine - a unique extract from Spirulina isolated through our patented extraction process. Mesenkine supports the migration and homing of stem cells by balancing key messengers involved in stem cell function.

  • Through multiple clinical trials StemEnhance Ultra was documented to optimize stem cell function in the body by increasing the number of both CD34+ stem cells and Endothelial Progenitor Cells (EPCs) in the blood circulation, supporting optimum renewal and repair of tissues and organs.

  • StemEnhance Ultra assists the body's inherent ability for long-term self-renewal by supporting the body's natural release of bone marrow stem cells.

  • StemEnhance Ultra is the result of 16 years of research and constitutes the most efficacious and scientifically proven stem cell support product on the market today.

  • StemEnhance Ultra FAQ
We need vitamins, minerals and antioxidants to nourish our cells and we need alkaline water to flush away toxins. But none of this rebuilds the body. None of this can actually bring back new tissue, bone, organs, or any part of the body. Science has just recently discovered that the only system known to actually rebuild the body is your own adult stem cells. If they are not releasing into the bloodstream as they should, your health will suffer.

It's as simple as that.

StemEnhance Ultra: Proven Clinical Studies

Through multiple clinical trials, StemEnhance Ultra was documented to optimize stem cell function in the body by increasing the number of both stem cells and Endothelial Progenitor Cells (EPCs) in the blood circulation, supporting optimum renewal and repair of tissues and organs.

StemEnhance Ultra Studies
Placebo did not show any significant effect on the number of circulating stem cells, StemEnhance triggered a transient increase in the number of CD34++ cells (25%) and a long-lasting increase in the number of circulating EPC (>75%).

StemEnhance Ultra Studies
Consumption of Fucoidan from Undaria Pinnatifida led to an increase in the background level of circulating stem cells.

StemEnhance Ultra Proven Clinical Studies

Mobilization of human stem cells study published in the Journal of Cardiovascular Revascularization Medicine

StemEnhance does not promote tumor growth study published in AntiCancer Research Journal

Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells. Published in Experimental Hematology.

Mobilization of bone marrow stem cells with StemEnhance improves muscle regeneration in cardiotoxin-induced muscle injury published in Cell Cycle.

The Therapeutic Potential of Stimulating Endogenous Stem Cell Mobilization published in the Journal of Tissue Regeneration - From Basic Biology to Clinical Application.

Use of Stem Cell Mobilizer on Ankle Injuries to Expedite Recovery in Professional Soccer Players published in MOJ Cell Science & Report.

Fucoidan protects mesenchymal stem cells against oxidative stress and enhances vascular regeneration published in International Journal of Cardiology.

Therapies from Fucoidan; Multifunctional Marine Polymers published in Marine Drugs.

StemEnhance Ultra also contains Mesenkine that was shown to increase the blood concentration of G-CSF that plays a key role in stem cell release.

Study on effects of Mesenkine

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StemEnhance Ultra Frequently Asked Questions

What is StemEnhance Ultra?

StemEnhance Ultra concentrates and combines extracts from nature's most primitive superfoods, fresh water microalgae and marine macroalgae, proving the body with the ultimate in stem cell support.

Why is StemEnhance Ultra beneficial

StemEnhance Ultra assists the body's inherent ability for long-term self-renewal by supporting the body's natural release of bone marrow stem cells.

What are the ingredients in StemEnhance Ultra?

StemEnhance Ultra provides the ultimate in stem cell support containing a proprietary blend of highly concentrated extracts, including Fucoidan, Cerule's own exclusive patented ingredients, StemEnhance and Mesenkine.

StemEnhance Ultra (AFA concentrate) is shown to support the release of stem cells from the bone marrow.

Fucoidan (undaria pinnatifida) is a marine algae well known to support the immune system. Cerule's fucoidan comes from undaria harvested from pristine environments like the Tasman Sea and Patagonia. Fucoidan from undaria pinnatifida has been documented to increase the number of circulating stem cells.

Mesenkine is a unique extract from Spirulina, isolated through our patented extraction process, that supports the release and homing of stem cells by balancing key messengers involved in stem cell function.

StemEnhance Ultra does not contain dairy, wheat, gluten, peanut, soy, corn, or allergens. There are no artificial flavors or colors. It is 100% vegetarian, non-GMO, and free from herbicides and pesticides.

The StemEnhance Ultra supplement fact sheet can be viewed here.

What are stem cells and why are they considered important?

'The primary roles of adult stem cells in a living organism are to maintain and repair the tissue in which they are found.' http://stemcells.nih.gov/info/basics/4.html. Furthermore, stem cells released from the bone marrow can migrate to various tissues where they contribute to the process of tissue repair.

How do I take StemEnhance Ultra?

Suggested usage is 2 capsules, 1 to 2 times daily.

Can children consume StemEnhance Ultra?

The clinical studies were done using adults therefore we recommend StemEnhance Ultra for adult consumption, however there are no known contraindications for children.

Can pets consume StemEnhance Ultra?

StemEnhance Ultra is formulated for human consumption. We know of no reason that it may be harmful to pets. AFA and spirulina have been used in the pet nutrition industry for years. However, no studies have been done using the product for pet consumption. Please consult with your Veterinarian.

Is there research on StemEnhance Ultra?

StemEnhance Ultra is the result of 16 years of research and constitutes the most efficacious and scientifically proven stem cell nutrition product on the market.

Through multiple clinical trials, StemEnhance Ultra was documented to optimize stem cell function in the body by increasing the number of both stem cells and and Endothelial Progenitor Cells (EPCs) in the bloodstream, supporting optimum renewal and repair of tissues and organs.

StemEnhance Ultra also contains Mesenkine, that was shown to increase the blood concentration of G-CSF that plays a key role in stem cell release.

Is there a video explaining how StemEnhance Ultra works?


Video Transcription

'The story of the development and the discovery of StemEnhance started nearly 2 decades ago, when I started to investigate an aquatic botanical called aphanizomenon flos aquae, in short afa. Afa is a blue green algae in Klamath lake in southern Oregon. So my starting point was to do a survey, to do an over view of all the benefits reported by people consuming afa.

And it became very rapidly clear that people consuming afa reported benefits overall touching overall inflammation, touching the immune system and also many of the consumers of afa were reporting an increase in mental clarity, mental energy, an ability to concentrate, an overall feeling of well being. So we started the investigation and rapidly discovered that afa is a source of phycocyanin, which is the blue pigment in all blue-green algae.

Now phycocyanin was already known at the time to be one of the most potent anti-inflammatory molecules coming from the plant world. So it explained a lot of the benefits that people had touching inflammation. Now we identified in afa, a polysaccaride that supports various aspects of the immune system, and we identified a molecule called PEA.

PEA is a molecule that the brain makes naturally, whenever someone feels happy, content, satisfied. It is known in chemistry as the molecule of love, or the molecule of joy. A deficiency of PEA has been associated with low mood, reduced ability to concentrate, attention deficit and it could go down even to depression. An oral dose of PEA can really reverse these kinds of conditions.

So discovering that afa contains PEA really explained all the benefits that people had experienced over the years in terms of this feeling of well being or mental clarity. But as we we're doing all this work, a lot of people reported other benefits that we could not explain on the basis of these 3 compounds.

And from a scientific standpoint what was challenging was not only the extent of these benefits, but the wide variety of these benefits. People were reporting benefits on the skin, the liver, on pancreatic function, the lungs, joints, nervous system, on the retina. So the question was, what is it that this product is doing that touches so many different aspects of human health.

So over the years, we had many hypotheses that we tested in the lab, we got good data, but nothing that gave us that 'a ha' that discovery t tell us what the product is doing. Until one day, when a colleague of mine sent me an article and the title of the article was turning blood into brain. It was a study in which scientists had observed that stem cells in circulation in the blood stream had the ability migrate in the brain and to become brain cells.

Around the same time, other studies had been published showing that stem cells had the ability to also migrate into the heart and the liver and to become heart cells and liver cells. So what we started to think, Dr Jensen and I, was that if stem cells can become brain cells, heart cells and liver cells, why not pancreatic cells, skin cells, joint cells, lung cells, why not all the other types of cells of the body.

So on the basis of data existing in the scientific literature, we proposed in a journal called medical hypotheses, that indeed stem cells constitute the natural repair system of the body. But what we had in mind when we made that proposal is that if that turns out to be true, and it did turn out to be true, that's what stem cells are doing in the body, but if that is true, that means that a product that would support the natural role of stem cells should lead to various benefits in various people. And that's what we had with AFA.

So with this thought, we went to the lab and we tested afa with regard to its ability to trigger stem cell release from the bone marrow. And we discovered that indeed, afa contains a specific molecule that blocks an adhesion molecule on the surface of stem cells called l-selectin. And that triggers the release of stem cells from the bone marrow.

So afa contains an l-selectin blocker. So we developed a concentrate of afa that we call StemEnhance and the consumption of 2 capsules of StemEnhance triggers the release of stem cells from the bone marrow and leads to a significant increase in the number of circulating stem cells and all these stem cells can then participate in the natural process of tissue repair.

Now after developing the assets to quantify stem cells and discovering the natural of stem cells in the body it was obvious to Dr Jensen and I, that given that this is a natural part of human physiology it cannot be that there's only one plant having an effect on stem cells. So we then asked the question, what other plant has been known throughout history to be associated to many different kinds of health benefits. So the ideas is to go and test these plants in the lab with the hypothesis that maybe their mechanism of action is that they also trigger the release of stem cells from the bone marrow.

So we tested many plants, and we discovered one that also triggers release of stem cells from the bone marrow. It is a brown seaweed called undaria pinnatifida also known in Japanese cuisine as Wakame. So undaria contains a polysaccaride called fucoidan. The consumption of fucoidan from undaria pinnatifida increases the number of stem cells, the baseline number of stem cells over time as we consume the product everyday.

Now, when we discovered the effect of afa on stem cells and developed StemEnhance and all the afa produced by Cerule started to be used to produce stem enhance, then Cerule started to take a different direction with the development of a phycocyanin concentrate. They started to concentrate phycocyanin, not from afa, but from spirulina. And it became another product called Cyactiv, that we will talk about later.

But, as they developed Cyactiv, concentrated phycocyanin, they discovered that spirulina contains another compound, it is a yellow compound. This yellow compound has not yet been identified, but when we feed this compound to people, it increases the concentration of GCSF in the blood. GCSF is a compound very well known to trigger stem cell release from the bone marrow.

So StemEnhance Ultra is the blend of these 3 products, StemEnhance, the fucoidan from undaria pinnatifida and mesenkine, this yellow compound isolated from spirulina. So since these 3 product trigger the release of stem cells form the bone marrow using different mechanisms of action, it means that blending them gives a unique and strong synergy. So the consumption of 2 capsules of StemEnhance Ultra triggers a very significant release of stem cells from the bone marrow, increasing the number of stem cells in circulation by anywhere between 4 to 10 million new stem cells. And all these stem cells are available to participate in the process of tissue repair.

So StemEnhance Ultra is a unique product, probably one of the best products out there to support the natural process of tissue repair and tissue renewal in the body.'

What is the StemEnhance Ultra capsule made from?

As stated on the label, the vegetarian capsule is made from hypromellose. Hypromellose is cellulose derivative or plant fiber.

Is StemEnhance Ultra certified Kosher and Halal?

StemEnhance Ultra ingredients are certified Kosher.
It is not certified Halal.

What is the shelf-life of StemEnhance Ultra?

There is an expiration date at the bottom of each bottle. StemEnhance Ultra has a shelf life of 3 years from manufacturing. All bottles should be stored in a cool, dry place.

Can StemEnhance Ultra be consumed with other Cerule products and other nutrients?

Yes, the Cerule products can be consumed together and were designed to enhance the beneficial effects of each other. We know of no concerning interaction between the Cerule products and other nutritional supplements.

Are there any known nutrient-medication interactions?

Like many green foods, StemEnhance Ultra contains naturally occurring vitamin K, which could interfere with vitamin K blockers used to thin the blood, such as coumadin.

If you have any health condition and/or are using medication, then consult your attending health care provider before consuming any nutritional supplement.

For some people, due to their conditions and medications, they need to manage their intake of certain nutrients. Below are the amounts of naturally occurring nutrients found in the plant based ingredients within StemEnhance Ultra:

Vitamin K: around 20 ug per serving (2 capsules)
Iron: 0.34 mg per serving (2 capsules)
Iodine: around 4 ug per serving (2 capsules)
Sodium: 9.66 mg per serving (2 capsules)
PEA: >0.5%

Why does the StemEnhance Ultra label state 'consult your physician if you are pregnant or nursing?'

Pregnancy and nursing are considered special conditions. We recommend that your attending Doctor(s) be made aware of any and all supplements consumed during this time. At this time, we do not advise StemEnhance Ultra consumption during pregnancy.

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